The three giants in the goblin camp in Baldur's Gate 3 are not to be killed, because killing them will cause the entire goblin to become hostile, making subsequent tasks difficult to complete, so it is not recommended for players to kill them.
Answer: No killing
If you kill it, it will cause all the goblins to become hostile, so it is not recommended for players to kill it.
And the Big Three will also be used in the mission. If they are killed, it will affect subsequent missions.
Although a plot twist can occur after a kill, this twist is a very ordinary twist.
If you must kill it, then run directly after killing it without hesitation.